Brain Region and Sex Differences in Age Association With Brain Volume: A Quantitative MRI Study of Healthy Young Adults

There is evidence that some brain regions show age-associated volume decline and that men undergo more accelerated cerebral aging than women. However, limited information is available on age-associated changes during young adulthood. The authors performed quantitative magnetic resonance imaging in 116 healthy young adults (57 men, 59 women; age range: 18-49 years) to evaluate the relationship of age and sex with volumes of frontal and temporal...