Original paper

Enhanced Fatty Acid Flux Triggered by Adiponectin Overexpression

Volume: 153, Issue: 1, Pages: 113 - 122
Published: Jan 1, 2012
Abstract
Adiponectin overexpression in mice increases insulin sensitivity independent of adiposity. Here, we combined stable isotope infusion and in vivo measurements of lipid flux with transcriptomic analysis to characterize fatty acid metabolism in transgenic mice that overexpress adiponectin via the aP2-promoter (ADNTg). Compared with controls, fasted ADNTg mice demonstrated a 31% reduction in plasma free fatty acid concentrations (P = 0.008), a...
Paper Details
Title
Enhanced Fatty Acid Flux Triggered by Adiponectin Overexpression
Published Date
Jan 1, 2012
Volume
153
Issue
1
Pages
113 - 122
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