Conditional Probability of Reclassification in an Active Surveillance Program for Prostate Cancer

We evaluated the risk of prostate cancer reclassification by time on active surveillance.From 1995 to 2014 we evaluated 557 and 251 men at very low and at low risk, respectively, who were on active surveillance and compliant with prostate biopsies. Our primary study outcome was reclassification to higher risk disease by grade or extent. Freedom from reclassification was estimated using the Kaplan-Meier approach with adjustment for covariates...