#1Thilo Westhofen(LMU: Ludwig Maximilian University of Munich)H-Index: 2
#2Alexander Buchner(LMU: Ludwig Maximilian University of Munich)H-Index: 31
Last. Alexander Kretschmer(LMU: Ludwig Maximilian University of Munich)H-Index: 18
view all 0 authors...
PURPOSE The optimal timing of radiotherapy (RT) after radical prostatectomy (RP) remains controversial with unknown impact on health-related quality of life (HRQOL). We aimed to compare the influence of early RT (eRT) and deferred RT (dRT) on HRQOL. METHODS 4511 patients were analysed. Inclusion criteria encompassed: ≥pT3, ISUP-grade ≥4, or positive surgical margin. A 1:4 propensity-score-matched-analysis of n=1599 patients was conducted [n=307: eRT, ≤6month after RP; n=1292: dRT, >6month after ...
#1Patrick J. Hensley(University of Texas MD Anderson Cancer Center)H-Index: 5
#2Kelly K. Bree(University of Texas MD Anderson Cancer Center)H-Index: 4
Last. Charles C. Guo(University of Texas MD Anderson Cancer Center)H-Index: 36
view all 0 authors...
Purpose null Data from the pre-neoadjuvant chemotherapy (NAC) era suggests patients who progress on BCG to muscle-invasive bladder cancer (P-MIBC) exhibit worse outcomes compared to de novo MIBC (D-MIBC). Herein, we investigate whether P-MIBC is an independent poor risk factor in the setting of contemporary NAC use. null Materials and methods null A review of patients who underwent radical cystectomy (RC) for cT2-3 MIBC from 2005-2018 was performed. Patients were stratified into high-risk (lymph...
PURPOSE To assess the prevalence and risk factors of male AUS mechanical failures and non-mechanical failures. MATERIALS AND METHODS The charts of all male patients who underwent AUS implantation between 2004 and 2020 in 16 centres were retrospectively reviewed. Patients with neurogenic stress urinary incontinence (SUI) were excluded as well as revisions/explantations due to infections and/or erosions. The causes of revision were divided into mechanical failures (fluid loss or malfunction from a...
PURPOSE To determine if testicular histopathologic heterogeneity is associated with sperm retrieval rates (SRRs) in non-obstructive azoospermic (NOA) men undergoing microdissection testicular sperm extraction (mTESE). MATERIALS AND METHODS All patients undergoing mTESE by a single, high-volume surgeon at a tertiary infertility referral center between 2010-2020 were evaluated. Pathology reports from testis biopsy at the time of mTESE reported by fellowship-trained genitourinary pathologists were ...
PURPOSE We aimed to understand the reasons patients choose to pursue third line overactive bladder (OAB) therapy. MATERIALS AND METHODS We conducted a mixed methods study that included patient interviews and survey data. Eligible patients were diagnosed by symptoms, had tried behavioral modifications, and OAB medications enrolled from October 2018 to August 2019. In addition to interviews, patients completed four surveys: the Pelvic Floor Distress Inventory (PFDI-20), Overactive Bladder Question...
OBJECTIVES To compare urinary tract infection (UTI) symptom resolution rates at 7-10 days in symptomatic women randomized to treatment based on standard urine culture (SUC) versus expanded quantitative urine culture (EQUC) results. METHODS Women ≥18 years old who responded "yes" to "do you feel you have a UTI?" agreed to urethral catheterization, and follow-up. Symptoms were assessed using the validated UTI Symptom Assessment (UTISA) questionnaire. Culture method was randomized 2:1 (SUC:EQUC); a...
PURPOSE Measurement of testosterone levels during androgen deprivation therapy (ADT) is broadly recommended, but how therapy should be altered in response to testosterone values during ADT remains controversial. Our objective was therefore to evaluate the relation between testosterone and concomitant prostate specific antigen (PSA) levels during ADT on clinical outcomes. MATERIAL AND METHODS Patients from the continuous androgen deprivation (CAD) arm of the PR.7 trial of intermittent ADT for bio...
Introduction null Radical cystectomy (RC) for the management of muscle-invasive bladder cancer remains a morbid procedure with high rates of perioperative complications. The role of pre-operative immuno-nutritional supplementation (Pre-INS) in improving post-RC outcomes is promising and needs further validation. null Materials and methods null We performed a retrospective review of 204 patients who underwent RC for bladder cancer at a single institution, comparing patients who received oral L-ar...
Introduction null Salvage prostatectomy (SRP) is rare due to the risk of postoperative complications. We compare salvage Retzius-sparing robotic-assisted radical prostatectomy (SRS-RARP) with salvage standard robotic-assisted radical prostatectomy (SS-RARP). null Materials and methods null 72 patients across 9 centers were identified (40 SRS-RARP vs. 32 SS-RARP). Demographics, perioperative data, and pathologic and functional outcomes were compared using student's t-test and ANOVA. Cox proportio...