Transfusion Criteria for Fresh Frozen Plasma in Liver Resection

To establish transfusion criteria for use of fresh frozen plasma (FFP) in liver resection.Fresh frozen plasma has been transfused in liver resection without adequate supporting evidence, leading to unnecessary use.Prospective study using a phase 1 dose-escalation, 3 + 3 cohort expansion design, modified for FFP transfusion. We designated a serum albumin level of 3.0 g/dL (step 1) as the starting limit for no transfusion and reduced the level in...