AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential
Volume: 12, Issue: 6a, Pages: 2511 - 2518
Published: Dec 1, 2008
Abstract
p97/VCP, a member of the AAA-ATPase super family, has been associated with a wide variety of essential cellular protein pathways com prising: (i) nuclear envelope reconstruction, (ii) cell cycle, (iii) Golgi reassembly, (iv) suppression of apoptosis and (v) DNA-damage response [1-6]. In addition, vasolin-containing protein (VCP) dislodges the ubiquitinated proteins from the endoplasmic reticulum (ER) and chaperones them to the cytosol for...
Paper Details
Title
AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential
Published Date
Dec 1, 2008
Volume
12
Issue
6a
Pages
2511 - 2518
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