Differential connexin expression in preglomerular and postglomerular vasculature: Accentuation during diabetes

Gap junctions may play an important role in regulating renal blood flow and glomerular responses. We have therefore made a comprehensive analysis of connexin expression in the renal vasculature of control and diabetic mice since elevated glucose has been reported to down-regulate connexin 43 in vascular cells in vitro.Connexin distribution was determined with immunohistochemistry using subtype-specific and cell type-specific antibodies. Diabetes...