Reduced expression of C1q-mRNA in monocytes from patients with systemic lupus erythematosus
Volume: 146, Issue: 3, Pages: 409 - 416
Published: Oct 13, 2006
Abstract
Inherited C1q deficiency is associated strongly with the development of systemic lupus erythematosus (SLE). The aim of our study was to evaluate the ability of monocytes from SLE patients without inherited C1q deficiency to up-regulate C1q-mRNA upon stimulation. Furthermore, we wanted to elucidate the physiological stimulus for up-regulation of C1q-mRNA. Peripheral blood mononuclear cell (PBMC)-derived monocytes from 10 SLE patients, 10 patients...
Paper Details
Title
Reduced expression of C1q-mRNA in monocytes from patients with systemic lupus erythematosus
Published Date
Oct 13, 2006
Volume
146
Issue
3
Pages
409 - 416
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