Designing a tubular matrix of oriented collagen fibrils for tissue engineering

A scaffold composed entirely of an extracellular matrix component, such as collagen, with cellular level control would be highly desirable for applications in tissue engineering. In this article we introduce a novel, straightforward flow processing technique that fabricates a small diameter tubular matrix constructed of anisotropic collagen fibrils. Scanning electron microscopy confirmed the uniform alignment of the collagen fibrils and...