Edaravone Ameliorates Oxidative Damage Associated with Aβ25-35 Treatment in PC12 Cells

Volume: 50, Issue: 3, Pages: 494 - 503
Published: Feb 8, 2013
Abstract
Oxidative damage is an important mediator of Alzheimer’s disease (AD); hence, antioxidant therapy is a potential treatment for AD. Edaravone, a free radical scavenger, has been shown to have neuroprotective properties. The study aimed to examine the effects of edaravone on indicators of Aβ25-35-induced oxidative damage in PC12 cells. PC12 cells were treated with 20, 40, or 80 μM edaravone before treatment with 30 μM Aβ25-35. After treatment, the...
Paper Details
Title
Edaravone Ameliorates Oxidative Damage Associated with Aβ25-35 Treatment in PC12 Cells
Published Date
Feb 8, 2013
Volume
50
Issue
3
Pages
494 - 503
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