Cytotoxic Iridoids from the Roots of Patrinia scabra

Six new iridoid glucosides, patriridosides D–I (1–6), and one new iridoid, scabrol A (7), along with 12 known non-glycosidic and glycosidic iridoids (8–19), have been isolated from an ethanolic extract of the roots of Patrinia scabra. The cytotoxic activity of the isolated compounds against human cervical carcinoma HeLa cells and gastric carcinoma MNK-45 cells was evaluated using the MTT assay. Compounds 1, 4–6, 8, and 18 showed cytotoxic...