Original paper
Antimalarial diterpene alkaloids from the seeds of Caesalpinia minax
Abstract
Two new diterpene alkaloids, caesalminines A (1) and B (2), possessing a tetracyclic cassane-type furanoditerpenoid skeleton with γ-lactam ring, were isolated from the seeds of Caesalpinia minax. Their structures were determined by different spectroscopic methods and ECD calculation. The plausible biosynthetic pathway of caesalminines A and B was proposed. The anti-malarial activity of compounds 1 and 2 is presented with IC50 values of 0.42 and...
Paper Details
Title
Antimalarial diterpene alkaloids from the seeds of Caesalpinia minax
Published Date
Jun 1, 2014
Journal
Volume
95
Pages
234 - 239
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Notes
History