Fitoterapia
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#1Jin-Tao Ma (SCUN: South Central University for Nationalities)
#2Jiao-Xian Du (SCUN: South Central University for Nationalities)H-Index: 2
Last. Juan He (SCUN: South Central University for Nationalities)H-Index: 9
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Abstract null null Kiwi (Actinidia chinensis) plants are severely destroyed by canker disease which is caused by the bacterium Pseudomonas syringae pv. actinidiae (Psa). This program tries to find anti-Psa agents among secondary metabolites of endophytic fungi from kiwi plant itself. The chemical investigation on one kiwi endophytic fungi, Fusarium tricinctum, resulted in the isolation of nine new imidazole alkaloids, fusaritricines A-I (1–9) together with seven known analogues (10–16). The stru...
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#1Xue-Jiao Wang (Fudan University)H-Index: 1
#2Sheng-Zhou Yu (JU: Jiangnan University)
Last. Jin-Feng Hu (School of Advanced Study)H-Index: 20
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Abstract null null Three labdane-type [multisins A–C (1–3)], two guaiane-type [multisins D (4) and E (5)], and one eudesmane-type [multisin F (6)] previously undescribed terpenoids, together with 14 mono- (7–20) and seven dimeric- (21–27) known terpenoids, were isolated from the 90% MeOH extract of the whole plant of Chloranthus multistachys. Their structures and absolute configurations were determined by extensive spectroscopic methods and electronic circular dichroism (ECD) calculations. Compo...
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Abstract null null Adhesion of monocytes to endothelial cells is an important initiating step in atherogenesis. One of the most abundant flavonoids in the diet, quercetin has been reported to inhibit monocyte adhesion to endothelial cells. However, it is poorly absorbed in the upper gastrointestinal tract during oral intake but rather is metabolized by the intestinal microbiota into various phenolic acids. Since the biological properties of the microbial metabolites of quercetin remain largely u...
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#1Xi Wang (WHU: Wuhan University)
Last. You-Sheng Cai (WHU: Wuhan University)H-Index: 7
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Abstract null null Japonisine A, a novel fawcettimine-type Lycopodium alkaloid with an unusual skeleton and two new fawcettimine-type ones, along with 20 known Lycopodium alkaloids, were isolated from the whole plants of Lycopodium japonicum Thunb. Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, and HR-ESIMS, as well as by comparison with the literature data. Notably, japonisine A (1) was the first example of fawcettimine-related Lycopodium alkaloid...
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#1Changkang Li (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 5
#2Hong-Qing Wang (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 12
Last. Jie Kang (CAMS&PUMC: Chinese Academy of Medical Sciences & Peking Union Medical College)H-Index: 14
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Abstract null null Eight previously undescribed compounds, two quinones (1–2), one sesquiterpene (3), and five phenol compounds (4–8), including three enantiomers (6a, 7a, and 8a), along with three corresponding known enantiomers (6b–8b) were isolated from the aerial parts of Morinda umbellata L. Their structures were elucidated by 1D and 2D NMR spectroscopy, X-ray diffraction, and experimental and calculated ECD spectra, respectively. Compound 5 was found to have weak cytotoxity, which inhibite...
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#1Mingyang Song (LNUTCM: Liaoning University of Traditional Chinese Medicine)
#2Zhengming Ying (LNUTCM: Liaoning University of Traditional Chinese Medicine)
Last. Guanlin Yang (LNUTCM: Liaoning University of Traditional Chinese Medicine)H-Index: 3
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Abstract null null Three novel alkaloids, identified as (E)-N-((2R)-3-(2,5-dihydroxy-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-hydroxypropanoyl)-3-(4-hydroxyphenyl)acrylamide (1), named oleracrylimide A, (E)-N-((2R)-3-(2,5-dihydroxy-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-hydroxypropanoyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide (2), named oleracrylimide B, and (E)-N-((2R)-3-(2,5-dihydroxy-4-((3,4,5-trihydroxy-6-(((3,4,5-tri...
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#1Thinley Gyeltshen (UTAS: University of Tasmania)
#2Gregory J. Jordan (UTAS: University of Tasmania)H-Index: 54
Last. Alex C. Bissember (UTAS: University of Tasmania)H-Index: 17
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Abstract null null The first natural product isolation studies of Nothofagus gunnii (Hook.f.) Oerst and Nothofagus cunninghamii (Hook.f.) Oerst have been undertaken. A previously unreported stilbene derivative, pinosylvin monoacetate, was isolated from the leaves of N. gunnii, in addition to 14 known compounds; including the flavonoids galangin, pinobanksin, catechin and quercetin; sesquiterpenoids such as, ilicol and (+)-β-costol acetate; 2,4-dihydroxy-6-methoxychalcone and pinosylvin. Four kno...
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#1Yun-Lai Liu (NCU: Nanchang University)H-Index: 1
#2Yong Wang (NCU: Nanchang University)H-Index: 2
Last. Zhi-Wang Zhou (NCU: Nanchang University)H-Index: 5
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Abstract null null Two new isoquinoline alkaloids, cryptowrayines A (1) and B (2), along with one known pavine alkaloid (-)-12-hydroxyeschscholtzidine (3), were isolated from the twigs of Cryptocarya wrayi. The structures of new compounds were elucidated by extensive spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Both compounds 1 and 2 exhibited moderate quinone reductase inducing activity in Hepa 1c1c7 cells.
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#1Benqin TangH-Index: 4
#2Zi-wei Li (JNU: Jinan University)
Last. Xiao-Qi Zhang (JNU: Jinan University)H-Index: 21
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Abstract null null Four new iboga-type alkaloids, ervaoffines H K (1–4), along with five known compounds were obtained from the aerial parts of Ervatamia officinalis. The absolute configurations of 1–4 were confirmed by X-ray diffraction and electronic circular dichroism (ECD) analyses. The isolates were tested for their anti-inflammatory activity. Compounds 1, 5, 6, and 9 showed potential inhibitory effect of NO production in LPS-stimulated BV2 and RAW264.7 cells.
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#1Yinan Zhang (Tianjin University of Science and Technology)H-Index: 3
#2Xiaoting Zhang (Tianjin University of Science and Technology)
Last. Hua Sun (Tianjin University of Science and Technology)H-Index: 10
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Abstract null null Since glucolipid metabolism disorders is often the mono-target therapy fails in managing blood glucose and lipid levels and the other complications, it is urgent and necessary to seek for the new potential drugs or functional food acting on multi-targets. The hypoglycemic and hypolipidemic dual activities of the root, stems and leaves of Dicyema caudatum, which is used for traditional Chinese medicine, was evaluated. Twelve extracts with different extraction conditions were pr...
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