Papers 5640
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#1Li Lianchun (CAS: Chinese Academy of Sciences)H-Index: 3
#2De-Sheng Ning (CAS: Chinese Academy of Sciences)H-Index: 6
Last. Zheng-Hong Pan (CAS: Chinese Academy of Sciences)H-Index: 13
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Illicium difengpi is well-known as its stem barks that have been widely used in the Traditional Chinese Medicine (TCM) for therapy rheumatoid arthritis and traumatic injury. To comprehensive utilization of resources, the phytochemical investigation on the branches and leaves of this plant was carried out, which led to the isolation of an undescribed neolignan along with three known lignans. Their structures were elucidated on the basis of extensive spectroscopic data and the new compound was elu...
Abstract null null Infectious diseases are reported to be one of the major causes of death in the world. The World Health Organization (WHO) warns of an increase in the deaths number because of antibacterial resistance. Lately, a trend towards searching for new active antibacterial compounds in plants has been observed. Ilex paraguariensis, known as Yerba Mate, is a plant known to be rich in numerous bioactive compounds that have an important role in human health. In this study, Yerba Mate was e...
#1M.J. Lim Ah Tock (TUT: Tshwane University of Technology)H-Index: 1
#2Weiyang Chen (TUT: Tshwane University of Technology)H-Index: 14
Last. Alvaro Viljoen (TUT: Tshwane University of Technology)H-Index: 57
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Abstract The South African Salvia species, Salvia africana-lutea, S. lanceolata and S. chamelaeagnea, are widely used to treat fever and inflammation associated with skin and lung infections. The aim of this study was to explore the non-volatile secondary metabolites and the phytochemical variation within these lesser known species, to support product development and commercialisation. Chemical profiles of the methanol extracts of 81 wild-harvested samples were obtained using ultra performance-q...
#1Jiawei Sun (Peking Union Medical College)
#2Jimei Liu (Peking Union Medical College)H-Index: 12
Last. Jungui Dai (Peking Union Medical College)H-Index: 21
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Abstract Dengratiol A (1), an unprecedented bibenzyl derivative bearing a tropolone unit together with three pairs of bibenzyl enantiomers (±)-dengratiols B–D [(±)-2–(±)-4], were isolated from Dendrobium gratiossimum Rchb.f. The resolution of enantiomers was performed with chiral HPLC. Their structures were characterized by extensive spectroscopic data analysis and calculated electronic circular dichroism (ECD). A hypothetical biosynthetic pathway for 1 is proposed. Biological assay revealed tha...
#1Bao Chen (CAS: Chinese Academy of Sciences)H-Index: 1
#2Wang-Sheng Li (CAS: Chinese Academy of Sciences)H-Index: 1
Last. Yue-Wei Guo (CAS: Chinese Academy of Sciences)H-Index: 38
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Abstract A detailed chemical investigation of two specimen of South China Sea sponges Halichondria sp. (No. 19-XD-47 and No. 17-XD-87) have resulted in the isolation of three new sterols, namely, halichsterols A (1), B (2) and C (3), together with seven related known ones (4–10). Their structures were determined by extensive spectroscopic analysis and by comparison with the spectral data reported in the literature. In bioassay, compound 2 displayed significantly anti-inflammatory activity in lip...
#1Xuehai Zhang (Guangdong Pharmaceutical University)
#2Yi Wang (Guangdong Pharmaceutical University)H-Index: 1
Last. Xiangjiu He (Guangdong Pharmaceutical University)H-Index: 15
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Abstract Lychee is a favorite fruit of the Cantonese and native to Southeast Asia. In this study, the anti-neuroinflammatory bioactive compounds of lychee seeds have been carried out. Five new jasmonates (1, 2, 6–8) and seventeen known compounds were isolated using a series of chemical and chromatographic methods. Their chemical structures were identified through comprehensive spectroscopic analysis. Anti-neuroinflammatory activities were assayed and evaluated for the purified compounds. Most of...
#1Seethapathy G Saroja (University of Trans-Disciplinary Health Sciences and Technology)
#2Christian Winther Wold (University of Oslo)H-Index: 3
Last. Helle Wangensteen (University of Oslo)H-Index: 17
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The resin of Canarium strictum Roxb. is used for rheumatism and asthma; the bark is used as a mosquito repellent. The major compounds in the resin are triterpenoids, but as no studies have been performed on the bark, this study investigated this economically important resource. Ten folk healers were interviewed about their medicinal uses of C. strictum. Resin and bark were extracted with dichloromethane followed by methanol using accelerated solvent extraction. The extracts were fractionated usi...
#1Xing Peng (SYSU: Sun Yat-sen University)
#2Qingyun Tan (SYSU: Sun Yat-sen University)H-Index: 1
Last. Qiong Gu (SYSU: Sun Yat-sen University)H-Index: 22
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Abstract null null Ferroptosis is a new type of cell death, which involves central neuronal system. Inhibition of ferroptosis is a promising strategy to prevent and treat neurological diseases. Thirteen phloroglucinols (1−13) were obtained from the whole plants of Hypericum japonicum. Of them, compounds 1–3 are new ones. Their structures were elucidated by extensive analysis of spectroscopic data and X-ray diffraction. All the isolates were evaluated for their inhibitory effect on RSL3-induced f...
#1Jian Sui (CAS: Chinese Academy of Sciences)
#2Chun-Ping Tang (CAS: Chinese Academy of Sciences)H-Index: 23
Last. Yang Ye (CAS: Chinese Academy of Sciences)H-Index: 32
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Abstract Four pairs of undescribed racemic bi(9,10-dihydro) phenanthrene and phenanthrene/bibenzyl atropisomers, bletistriatins A-D (1–4), along with 22 known compounds were isolated from the rhizomes of Bletilla striata. These dimeric derivatives were constructed through direct C C connection or an oxygen bridge. The structures of new compounds were fully established by extensive analysis of MS, and 1D and 2D NMR spectroscopic data. Owing to sterically hindered rotation around the biaryl axis, ...
#1Zha Rui (Guangdong Pharmaceutical University)
#2Enhui Ge (Guangdong Pharmaceutical University)
Last. Tao Liu (Guangdong Pharmaceutical University)H-Index: 8
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Abstract Macamides are a class of bioactive amide alkaloids found only in maca (Lepidium meyenii). Recent studies have shown that macamide-rich extracts possess various biological activities, such as antioxidative, immune-enhancing, and reproductive health-improving activities. In the present study, N-benzyl docosahexaenamide (NB-DHA), a newly identified macamide with the highest degree of unsaturation among all identified macamides, was identified from the maca extract. Microalgae oil, a docosa...
Top fields of study
Traditional medicine