Dendrimer design using CuI-catalyzed alkyne–azide “click-chemistry”

The chemoselective [3+2] cycloaddition of an azide on to an alkyne, catalyzed by Cu1, has become known as “click-chemistry”. The ease with which this reaction can be carried out and the formation of pure product without the need for further purification, offer a tremendous potential in developing monodisperse 1,4-disubstituted 1,2,3-triazole heterocycle based macromolecules of a diverse nature. The versatility of this approach in designing...