Original paper
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
Abstract
Intestinal microbes provide multicellular hosts with nutrients and confer resistance to infection. The delicate balance between pro- and anti-inflammatory mechanisms, essential for gut immune homeostasis, is affected by the composition of the commensal microbial community. Regulatory T cells (Treg cells) expressing transcription factor Foxp3 have a key role in limiting inflammatory responses in the intestine. Although specific members of the...
Paper Details
Title
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
Published Date
Nov 13, 2013
Journal
Volume
504
Issue
7480
Pages
451 - 455
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Notes
History