Characterization and pharmacokinetic analysis of aerosolized aqueous voriconazole solution
Volume: 72, Issue: 1, Pages: 199 - 205
Published: May 1, 2009
Abstract
Invasive fungal infections in immunocompromised patients have high mortality rates despite current treatment modalities. This study was designed to evaluate the suitability of an aqueous solution of voriconazole solubilized with sulfobutyl ether-β-cyclodextrin for targeted drug delivery to the lungs via nebulization. A solution was prepared such that the inspired aerosol dose was isotonic with an acceptable mass median aerodynamic diameter of...
Paper Details
Title
Characterization and pharmacokinetic analysis of aerosolized aqueous voriconazole solution
Published Date
May 1, 2009
Volume
72
Issue
1
Pages
199 - 205
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