Review paper

ΔFosB: A sustained molecular switch for addiction

Volume: 98, Issue: 20, Pages: 11042 - 11046
Published: Sep 25, 2001
Abstract
The longevity of some of the behavioral abnormalities that characterize drug addiction has suggested that regulation of neural gene expression may be involved in the process by which drugs of abuse cause a state of addiction. Increasing evidence suggests that the transcription factor DeltaFosB represents one mechanism by which drugs of abuse produce relatively stable changes in the brain that contribute to the addiction phenotype. DeltaFosB, a...
Paper Details
Title
ΔFosB: A sustained molecular switch for addiction
Published Date
Sep 25, 2001
Volume
98
Issue
20
Pages
11042 - 11046
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