NAD+ levels and glucose uptake of cultured human epidermal cells exposed to sulfur mustard
Abstract
In cultured human epidermal cells exposure to the vesicant sulfur mustard (HD) causes a decrease of the NAD+ content, which depends on the dose and the time period between exposure to HD and NAD+ measurement. Presumably, this NAD+ loss is due to activation of the enzyme NAD:protein ADP-ribosyltransferase (ADPRT) and may lead to glycolysis inhibition, disturbance of energy metabolism, and eventually cell death. Since prevention of this NAD+...
Paper Details
Title
NAD+ levels and glucose uptake of cultured human epidermal cells exposed to sulfur mustard
Published Date
Mar 1, 1989
Volume
98
Issue
1
Pages
159 - 165
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