A randomised comparison of Cartomerge vs. NavX fusion in the catheter ablation of atrial fibrillation: The CAVERN Trial

Published on Mar 1, 2012in Journal of Interventional Cardiac Electrophysiology1.9
路 DOI :10.1007/S10840-011-9632-7
Kim Rajappan18
Estimated H-index: 18
(St Bartholomew's Hospital)
Purpose Integration of a 3D reconstruction of the left atrium into cardiac mapping systems can aid catheter ablation of atrial fibrillation (AF). The two most widely used systems are NavX Fusion and Cartomerge. We aimed to compare the clinical efficacy of these systems in a randomised trial.
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Purpose Pulmonary vein antrum isolation (PVAI) guided by intracardiac echocardiography and a roaming circular mapping catheter is an effective treatment modality for atrial fibrillation. Unfortunately, the complexity of this technique leads to long procedure times and high fluoroscopy exposure. This study examined the effect of two different mapping systems on the procedural characteristics and clinical outcomes of PVAI for atrial fibrillation.
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Aims The aim of this study was to investigate whether circumferential pulmonary vein (PV) isolation guided by image integration improves the procedural and clinical outcomes of atrial fibrillation (AF) ablation in comparison with segmental PV isolation and circumferential PV isolation guided by three-dimensional (3D) electroanatomical mapping alone. Methods and results Procedural and clinical outcomes of 573 patients who underwent their first catheter ablation for paroxysmal AF between January 2...
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Over the years, various imaging modalities have been used to guide ablation procedures. Technology has rapidly progressed from Two-dimensional fluoroscopic imaging to several different forms of 3D mapping systems using magnetic and impedance sensors, as well as automated imaging components derived from computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, and rotational angiography. These have provided greater anatomic detail for accurate ablation. However, ablation outcomes re...
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Aims A detailed appreciation of the left atrial/pulmonary venous (LA/PV) anatomy may be important in improving the safety and success of catheter ablation for AF. The aim of this randomized study was to determine the impact of computed tomographic (CT) integration into an electroanatomic mapping (EAM) system on clinical outcome in patients undergoing catheter ablation for atrial fibrillation (AF). Methods and results Eighty patients with AF were randomized to undergo first-time wide encirclement...
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#1Yuan Zhong (Tongji University)H-Index: 1
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#1Lixia Shu (Capital Medical University)
#2Jin Wang (Capital Medical University)
Catheter navigation guided by the registration of electroanatomic map (EAM) and CT surface is widely used in atrial fibrillation (AF) ablations, however, few studies have done on the registration algorithm. Moreover, some of them are semiautomatic that physicians must be professional; some are inaccurate for catheter navigation. A both automatic and accurate registration method is needed. Therefore, in this study, we proposed a traditional iterative closest point (ICP) based approach for EAM and...
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#1Caspar Gruijthuijsen (Katholieke Universiteit Leuven)H-Index: 9
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Catheter navigation is typically based on fluoroscopy. This implies exposure to harmful radiation, lack of depth perception and limited soft-tissue contrast. Catheter navigation would benefit from guidance that makes better use of detailed pre-operatively acquired MR/CT images, while reducing radiation exposure and improving spatial awareness of the catheter pose and shape. A prerequisite for such guidance is an accurate registration between the catheter tracking system and the MR/CT scans. Exis...
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