Increased splenic fluorodeoxyglucose uptake in a patient with granulomatous angitis.

Published on Jan 1, 2007in Internal Medicine1.005
· DOI :10.2169/INTERNALMEDICINE.46.0098
Hiroshi Maruoka7
Estimated H-index: 7
(Kurume University),
Takeharu Koga13
Estimated H-index: 13
(Kurume University)
+ 4 AuthorsHisamichi Aizawa28
Estimated H-index: 28
(Kurume University)
Sources
Abstract
: Although utility of 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) has been rehearsed in large vessel vasculitides, it is not known if small vessel vasculitides are also associated with increased FDG uptake. Hereby described is a 64-year-old female patient with prolonged fever and splenomegaly, which was depicted as a hot area in FDG-PET. Splenectomy disclosed microaneurysms, giant cell granuloma, perivascular leukocytic infiltration with fibrinoid necrosis, consistent with granulomatous angitis. Serum myeloperoxidase-antineutrophil cytoplasmic antibody was positive. The present case illustrates that vasculitides affecting small vessels present increased FDG uptake as do those affecting large vessels.
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