SYSTOLIC ANTERIOR MOTION OF THE ANTERIOR MITRAL LEAFLET AND HYPERTROPHIC CARDIOMYOPATHY: A PREDICTOR OF NON-GENETIC, NON-FAMILIAL DISEASE?

Published on Mar 12, 2013in Journal of the American College of Cardiology24.093
· DOI :10.1016/S0735-1097(13)60532-X
Beth A. Medford2
Estimated H-index: 2
 (Mayo Clinic), Kristina H. Haugaa50
Estimated H-index: 50
 (Mayo Clinic)+ 7 AuthorsPatrick W. O'Leary41
Estimated H-index: 41
 (Mayo Clinic)
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Abstract
Hypertrophic cardiomyopathy (HCM) is marked by profound phenotypic and genotypic heterogeneity. Systolic anterior motion (SAM) of the anterior mitral leaflet is a classically described feature of HCM but its genetic predilection is unknown. Our study cohort consisted of 213 (74 male, mean age 51
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May 25, 2021·European Journal of Clinical Investigation4.69
#1Amir Aziz (U of A: University of Alberta)H-Index: 1
#2Szymon K. Musiol (North Bristol NHS Trust)H-Index: 1
Last. Gregory Y.H. Lip (University of Liverpool)H-Index: 202
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INTRODUCTION Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac condition and the most common cause of sudden cardiac death (SCD) in patients below the age of 35. Genetic testing is a vital part of HCM diagnostics, yet correlation with clinical phenotypes remains complex. Identifying clinical predictors of informative genetic testing may prevent unnecessary investigations and improve cost-effectiveness of services. This article reviews the current literature pertinent to iden...
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