Abstract null null Background null The benefit of optimal medical therapy (OMT) on 5-year outcomes in patients with 3-vessel disease and/or left main disease after percutaneous coronary intervention or coronary artery bypass grafting (CABG) was demonstrated in the randomized SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) trial. null null null Objectives null The objective of this analysis is to assess the impact of the status of OMT at 5 years on 10-year mortality after percutaneous...
An increasing number of people are now living with cardiovascular disease (CVD), with concomitant CVD-related hospitalizations, operations, and prescriptions. To ultimately deliver optimal cardiovascular care, access to population-based biobanks with data on multiomics, phenotypes, and lifestyle risk factors are crucial. UK Biobank is a cohort study that incorporated data between 2006 and 2010 from over half a million individuals (40 to 69 years of age) at recruitment from across the United King...
#2Husam M. Salah(University of Arkansas for Medical Sciences)H-Index: 8
Last. Sean A. Virani(UBC: University of British Columbia)H-Index: 17
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Abstract null null The lymphatic system is an integral part of the circulatory system and plays an important role in the volume homeostasis of the human body. The complex anatomy and physiology paired with a lack of simple diagnostic tools to study the lymphatic system have led to an underappreciation of the contribution of the lymphatic system to acute and chronic heart failure (HF). Herein, we discuss the physiological role of the lymphatic system in volume management and the evidence demonstr...
Last. Adolfo Correa(UMMC: University of Mississippi Medical Center)H-Index: 84
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Abstract null null Background null Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2, ASXL1, and JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). null null null Objectives null This study sought to evaluate whether CHIP is associated with incident HF. null null null Methods null CHIP status was obtained from whole exome ...