Original paper
Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB
Abstract
Cellular adaptation is the dynamic response of a cell to adverse changes in its intra/extra cellular environment. The aims of this study were to investigate the role of: (i) the glutathione antioxidant system, and (ii) the transcription factor EB (TFEB), a newly revealed master regulator of lysosome biogenesis, in cellular adaptation to nanoparticle-induced oxidative stress. Intracellular concentrations of glutathione species and activation of...
Paper Details
Title
Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB
Published Date
Apr 17, 2011
Journal
Volume
6
Issue
3
Pages
249 - 262