Papers 1,116
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#1Anna Bogdanska (TCD: Trinity College Dublin)H-Index: 1
#2Oliviero L. Gobbo (TCD: Trinity College Dublin)H-Index: 20
Last. Adriele Prina-Mello (TCD: Trinity College Dublin)H-Index: 35
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This article presents an automated image-processing workflow for quantitative assessment of SPION accumulation in tissue sections stained with Prussian blue for iron detection. We utilized supervised machine learning with manually labeled features used for training the classifier. Performance of the classifier was validated by 10-fold cross-validation of obtained data and by measuring Dice and Jaccard Similarity Coefficients between manually segmented image and automated segmentation. The propos...
#1Yun Ju Choi (PNU: Pusan National University)H-Index: 4
#2Jun Woo Park (PNU: Pusan National University)H-Index: 3
Last. Dae Youn Hwang (PNU: Pusan National University)H-Index: 23
view all 5 authors...
To assess the in vivo impact of nanoplastics (NP) and coagulation-based purified NP (PurNP), this study analyzed for alterations in the biodistribution, toxicity and inflammatory response in ICR mice exposed to three different doses of NP (5, 25, and 50 mg/kg) and PurNP for 2 weeks. Except water consumption, which was dose-dependently and significantly increased in all NP-treated groups, most factors assessed for feeding behaviors and excretions remained constant, without any significant change....
#1Andrea Rivero Arze (University of the West)H-Index: 1
#2Catherine Mouneyrac (University of the West)H-Index: 37
Last. Nicolas ManierH-Index: 12
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The widespread use and release of nanomaterials (NMs) in aquatic ecosystems is a concerning issue as well as the fate and behavior of the NMs in relation to the aquatic organisms. In this work, the freshwater microcrustacean Daphnia magna was exposed to 12 different and well-known NMs under the same conditions for 24 h and then placed in clean media for 120 h, in order to determine their different uptake and elimination behaviors. The results showed that most of the tested NMs displayed a fast u...
#1Sandeep Keshavan (KI: Karolinska Institute)H-Index: 8
#2Govind Sharan Gupta (KI: Karolinska Institute)H-Index: 11
Last. Bengt Fadeel (KI: Karolinska Institute)H-Index: 76
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Carbon nanotubes (CNTs) have been extensively investigated, and several studies have shown that multi-walled CNTs can trigger inflammation and fibrosis in animal models. However, while neutrophils ...
#1Zahra Behroozi (IUMS: Iran University of Medical Sciences)H-Index: 2
#2Behnaz Rahimi (IUMS: Iran University of Medical Sciences)H-Index: 1
Last. Fatemeh Ramezani (IUMS: Iran University of Medical Sciences)H-Index: 13
view all 8 authors...
Despite the widespread use of gold nanoparticles (GNPs), there is no consensus on their distribution to different tissues and organs. The present systematic review and meta-analysis addresses the accumulation of GNPs in brain tissue. Extensive searches were conducted in electronic databases, Medline, Web of Science, EMBASE, and Scopus. Based on inclusion and exclusion criteria, primary and secondary screening was performed. The value of brain accumulation of gold nanoparticle (the percentage of ...
#1Ilaria Zanoni (UNITS: University of Trieste)H-Index: 5
#2Matteo Crosera (UNITS: University of Trieste)H-Index: 19
Last. Francesca Larese Filon (UNITS: University of Trieste)H-Index: 24
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Children are potentially exposed to products that contain nanoparticles (NPs). In particular, silver NPs are commonly present both in products used by and around children, primarily due to their antibacterial properties. However, very few data are available regarding the ability of silver NPs to penetrate through the oral mucosa in children. In the present work, we used baby porcine buccal mucosa mounted on vertical Franz diffusion cells, as an in vitro model to investigate penetration of silver...
#1Boštjan Kokot (IJS: Jožef Stefan Institute)H-Index: 2
#1Boštjan Kokot (IJS: Jožef Stefan Institute)H-Index: 3
Last. Janez Štrancar (IJS: Jožef Stefan Institute)H-Index: 18
view all 10 authors...
Nanotechnologies hold great promise for various applications. To predict and guarantee the safety of novel nanomaterials, it is essential to understand their mechanism of action in an organism, causally connecting adverse outcomes with early molecular events. This is best investigated using noninvasive advanced optical methods, such as high-resolution live-cell fluorescence microscopy, which require stable labeling of nanoparticles with fluorescent dyes. However, as shown here, when the labeling...
#1Eun-Jung Park (Kyung Hee University)H-Index: 27
#2Min-Sung Kang (Kyung Hee University)H-Index: 8
Last. Youngmi Kim Pak (Kyung Hee University)H-Index: 37
view all 10 authors...
In our previous study, 20 nm-sized amorphous silica nanoparticles (20-SiNPs), but not 50 nm-sized amorphous silica nanoparticles (50-SiNPs), induced pulmonary inflammatory response in rats exposed repeatedly for 14 days (12.5, 25, and 50 μg/time, total six times). In this study, we tried to clarify the causes of different responses induced by both SiNPs using mice (12.5, 25, and 50 μg/lung) and mouse alveolar macrophage cells. When exposed to alveolar macrophage cells for 24 h, both SiNPs decrea...
#1Maria Assenhöj (LiU: Linköping University)
#2Peter Eriksson (LiU: Linköping University)H-Index: 30
Last. Karin Cederbrant (RISE: RISE Research Institutes of Sweden)
view all 9 authors...
Metal oxide nanoparticles are widely used in both consumer products and medical applications, but the knowledge regarding exposure-related health effects is limited. However, it is challenging to investigate nanoparticle interaction processes with biological systems. The overall aim of this project was to improve the possibility to predict exposure-related health effects of metal oxide nanoparticles through interdisciplinary collaboration by combining workflows from the pharmaceutical industry, ...
#1Chao Wang (NMU: Nanjing Medical University)H-Index: 10
#2Jiansheng Zhu (NMU: Nanjing Medical University)H-Index: 7
Last. Shoulin Wang (NMU: Nanjing Medical University)H-Index: 33
view all 9 authors...
This study attempts to explore the potential impact of titanium dioxide nanoparticles (n-TiO2) on bioconcentration and reproductive impairments of male zebrafish in the presence of 2,2',4,4'-tetrabromodiphenyl ether (BDE47), the congener of PBDEs predominant in environment and most abundant in biosamples. n-TiO2 nanoparticles strongly adsorbed BDE47 to form BDE47/TiO2 complex, which was taken up into the testes of zebrafish, and increased the tissue burdens of both BDE47 and n-TiO2. Correspondin...
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