Clinical Features and Colonic Motor Disturbances in Chronic Megacolon in Adults

Chronic megacolon is a rare disease of the colonic motor function characterized by a permanent increase in colonic diameter. We reviewed electronic medical records of all patients diagnosed with chronic megacolon from 1999 to 2014 at Mayo Clinic. Our aim was to summarize clinical and motility features, including colonic compliance and tone measured by colonic barostat-controlled 10-cm-long infinitely compliant balloon. Colonic compliance curves...