Digestive Diseases and Sciences
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#1Nneka N. Ufere (Harvard University)H-Index: 12
#2John Donlan (Harvard University)H-Index: 3
Last. Areej El-Jawahri (Harvard University)H-Index: 38
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Patients with end-stage liver disease (ESLD) experience frequent readmissions; however, studies focused on patients’ and caregivers’ perceptions of their transitional care experiences to identify root causes of burdensome transitions of care are lacking. To explore the transitional care experiences of patients with ESLD and their caregivers in order to identify their supportive care needs. We conducted interviews with 15 patients with ESLD and 14 informal caregivers. We used semi-structured inte...
2 CitationsSource
#1Jin Yong Kim (UOU: University of Ulsan)H-Index: 3
#1Jin Yong Kim (UOU: University of Ulsan)H-Index: 3
Last. Suk-Kyun Yang (UOU: University of Ulsan)H-Index: 65
view all 17 authors...
The Rutgeerts score is used to predict postoperative recurrence in CD patients after ileocolic resection and is primarily based on endoscopic findings at the neoterminal ileum. However, the optimal assessment of anastomotic ulcers (AUs) remains subject to debate. We aimed to investigate the association between anastomotic ulcers (AUs) and endoscopic recurrence in postoperative Crohn’s disease (CD) patients. This single-center retrospective study, conducted between 2000 and 2016, evaluated postop...
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#1Anthony A Xu (BCM: Baylor College of Medicine)H-Index: 1
#2Kristi L. Hoffman (BCM: Baylor College of Medicine)H-Index: 8
Last. Li JiaoH-Index: 35
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Systemic diseases have been associated with oral health and gut microbiota. We examined the association between oral health and the community composition and structure of the adherent colonic gut microbiota. We obtained 197 snap-frozen colonic biopsies from 62 colonoscopy-confirmed polyp-free individuals. Microbial DNA was sequenced for the 16S rRNA V4 region using the Illumina MiSeq, and the sequences were assigned to the operational taxonomic unit based on SILVA. We used a questionnaire to asc...
1 CitationsSource
#1Yuval A. Patel (Duke University)H-Index: 9
#2Jia Yao (Duke University)H-Index: 8
Last. Andrew J. Muir (Duke University)H-Index: 63
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Background Patients with chronic hepatitis C and risky/harmful alcohol use experience poor outcomes. Granular data evaluating whether alcohol counseling during hepatitis C treatment impacts longitudinal alcohol consumption are lacking. Aims To evaluate whether provider-delivered counseling in the context of direct-acting antiviral hepatitis C treatment associates with decreased longitudinal alcohol consumption. Methods We performed secondary data analysis from the Hep ART study including adults ...
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#1Christian P. Selinger (Leeds Teaching Hospitals NHS Trust)H-Index: 25
#2Helen Rafferty (Leeds Teaching Hospitals NHS Trust)H-Index: 1
Last. Clare Donnellan (Leeds Teaching Hospitals NHS Trust)
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The COVID-19 pandemic has created a public health emergency. In this context, there are major concerns for patients with inflammatory bowel disease (IBD), particularly for those treated with immunomodulators, biologics, and Janus Kinase inhibitors. Infection susceptibility is, in fact, one of the reported risks for immunotherapy drugs. This review provides the existing evidence from worldwide case series describing: (a) the risk for the SARS-CoV-2 infection and (b) the risk of a severe infection...
4 CitationsSource
#1Remo Panaccione (U of C: University of Calgary)H-Index: 83
#2John D. Isaacs (Newcastle upon Tyne Hospitals NHS Foundation Trust)H-Index: 80
Last. Chinyu Su (Pfizer)H-Index: 16
view all 9 authors...
Tofacitinib is an oral, small-molecule JAK inhibitor for the treatment of ulcerative colitis (UC). Creatine kinase (CK) levels and CK-related adverse events (AEs) in tofacitinib-treated patients with UC were evaluated. Data were analyzed for three UC cohorts: Induction (phase 2 and 3 induction studies); Maintenance (phase 3 maintenance study); Overall [patients who received tofacitinib 5 or 10 mg twice daily (b.d.) in phase 2, phase 3, or open-label, long-term extension studies; data at November...
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#1Youn I Choi (Gachon University)H-Index: 8
#2Kyoung Oh Kim (Gachon University)H-Index: 14
Last. Dong Kyun Park (Gachon University)H-Index: 16
view all 7 authors...
Background and aim Manual abdominal massage has been shown to effectively treat slow-transit constipation, but it is labor-intensive. To offer an alternative treatment option for constipation, the Bamk-001 automatic abdominal massage device was developed. The aim of this study was to assess the effect of the Bamk-001 device on symptom profiles and colon transit time (CTT) in patients with chronic constipation. Methods Thirty-seven patients with chronic functional constipation diagnosed using the...
1 CitationsSource
#1Fan Xiao (Capital Medical University)H-Index: 4
#2Meixin Gao (Capital Medical University)H-Index: 2
Last. Hongshan Wei (Capital Medical University)H-Index: 5
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Endoplasmic reticulum (ER) stress is one of the major causes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Our previous study showed that maintains the homeostasis of ER could effectively alleviate NAFLD. In this study, we found that the loss of FAM172A increased ER stress. The aims of this study were to explore whether FAM172A could improve NAFLD by inhibiting ER stress. The expression levels of FAM172A and ER stress were detected by western blot. The method of immunofluoresc...
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#1Sara van Gennep (UvA: University of Amsterdam)H-Index: 4
#1Sara van Gennep (UvA: University of Amsterdam)H-Index: 2
Last. Angela G. E. M. de Boer (PHRI: Public Health Research Institute)H-Index: 14
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Work-related aspects are important determinants of health for inflammatory bowel disease (IBD) patients. We aimed to describe quality of working life (QWL) in IBD patients and to assess variables that are associated with QWL. Employed IBD patients of two tertiary and two secondary referral hospitals were included. QWL (range 0–100) was measured using the Quality of Working Life Questionnaire (QWLQ). Work productivity (WP), fatigue, and health-related quality of life (HRQL) were assessed using th...
1 CitationsSource
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