Studies on the Constituents of Broussonetia Species VIII. Four New Pyrrolidine Alkaloids, Broussonetines R, S, T, and V and a New Pyrroline Alkaloid, Broussonetine U, from Broussonetia kazinoki SIEB.

Four new pyrrolidine alkaloids, broussonetines R, S, T, and V and a new pyrroline alkaloid, broussonetine U were isolated from the branches of Broussonetia kazinoki SIEB. (Moraceae) in low yield. Broussonetines R, S and T were formulated as (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-{(1R)-1-hydroxy-3-[6-(4-hydroxybutyl)-cyclohexy-2-on-1(6)-enyl]propyl} pyrrolidine (1), (2R, 3R, 4R, 5R)-2-hydroxymethyl-3, 4-dihydroxy-5-[(1R, 10S)-1, 10,...