Platelet Rho GTPases–a focus on novel players, roles and relationships
Abstract
Rho GTPases are critical for platelet function. Although the roles of RhoA, Rac and Cdc42 are characterized, platelets express other Rho GTPases, whose activities are less well understood. This review summarizes our understanding of the roles of platelet Rho GTPases and focuses particularly on the functions of Rif and RhoG. In human platelets, Rif interacts with cytoskeleton regulators including formins mDia1 and mDia3, whereas RhoG binds...
Paper Details
Title
Platelet Rho GTPases–a focus on novel players, roles and relationships
Published Date
Mar 6, 2015
Journal
Volume
466
Issue
3
Pages
431 - 442
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