Review paper
The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade
Abstract
ATP-binding cassette (ABC) transporters represent one of the largest and oldest families of membrane proteins in all extant phyla from prokaryotes to humans, which couple the energy derived from ATP hydrolysis essentially to translocate, among various substrates, toxic compounds across the membrane. The fundamental functions of these multiple transporter proteins include: (1) conserved mechanisms related to nutrition and pathogenesis in...
Paper Details
Title
The modulation of ABC transporter-mediated multidrug resistance in cancer: A review of the past decade
Published Date
Jan 1, 2015
Journal
Volume
18
Pages
1 - 17
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