Usefulness of Left Atrial Volume in Predicting First Congestive Heart Failure in Patients >65 Years of Age With Well-Preserved Left Ventricular Systolic Function
Left atrial (LA) volume is a barometer of diastolic dysfunction. Whether it predicts congestive heart failure (CHF) in patients with preserved left ventricular (LV) systolic function is not known. Olmsted County, Minnesota, residents aged ≥65 years referred for transthoracic echocardiography from 1990 to 1998, who were in sinus rhythm without a history of CHF were followed in the medical records to 2003 (mean follow-up duration 4.3 ± 2.7 years). Of the 1,495 patients identified, 1,375 (92%) with LV ejection fractions ≥50% (mean age 75 ± 7 years; 59% women) constituted the study population, 138 (10%) of whom developed CHF. Baseline LA volume ≥32 ml/m 2 was an independent predictor of first CHF (p 2 (p 37 ml/m 2 ) were 95%, 91%, and 83%, respectively (p
The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force on Practice Guidelines regularly reviews existing guidelines to determine when an update or full revision is needed. This process gives priority to areas where major changes in text, particularly recommendations,
Abstract We sought to determine the risk for the first episodes of atrial fibrillation (AF) and congestive heart failure (CHF) in a cohort of patients aged ≥65 years who had abnormal left ventricular (LV) diastolic relaxation. Records were reviewed for all residents of Olmsted County, Minnesota, who had ≥1 transthoracic echocardiogram performed at the Mayo Clinic between 1990 and 1998, and who were in sinus rhythm and did not have a history of AF, CHF, valvular or congenital heart disease, perma...
Since Framingham Heart Study investigators first confirmed the existence and importance of cardiac risk factors in 1961 [(1)][1], clinicians and scientists have been seeking to refine our ability to predict cardiovascular disease risk. These efforts stem from an appreciation that atherosclerosis
Last. James B. Seward(UR: University of Rochester)H-Index: 39
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Objectives We sought to determine if echocardiography enhances prediction of first age-related cardiovascular events. Background Whether echocardiographic assessment improves risk stratification for first cardiovascular events is not well known. Methods This retrospective cohort study included randomly selected residents of Olmsted County, Minnesota, age ≥65 years, who had ≥1 transthoracic echocardiograms at the Mayo Clinic between 1990 and 1998, in sinus rhythm, without valvular or congenital h...
Abstract Objectives The objective of this study was to determine whether diastolic dysfunction is associated with increased risk of nonvalvular atrial fibrillation (NVAF) in older adults with no history of atrial arrhythmia. Background Few data exist regarding the relationship between diastolic function and NVAF. Methods The clinical and echocardiographic characteristics of patients age ≥65 years who had an echocardiogram performed between 1990 and 1998 were reviewed. Exclusion criteria were his...
Heart failure (HF) is a major public health problem in the United States. Nearly 5 million patients in this country have HF, and nearly 500,000 patients are diagnosed with HF for the first time each year. The disorder is the underlying reason for 12 to 15 million office visits and 6.5 million hospital days each year (1). During the last 10 years, the annual number of hospitalizations has increased from approximately 550,000 to nearly 900,000 for HF as a primary diagnosis and from 1.7 to 2.6 mill...
References......2112 Heart failure (HF) is a major public health problem in the United States. Nearly 5 million patients in this country have HF, and nearly 500,000 patients are diagnosed with HF for the first time each year. The disorder is the underlying reason for 12 to 15 million office visits
Abstract Although congestive heart failure (CHF) is a common syndrome among the elderly, there is a relative paucity of population-based data, particularly regarding CHF with normal systolic left ventricular function. A total of 4,842 independent living, community-dwelling subjects aged 66 to 103 years received questionnaires on medical history, family history, personal habits, physical activity, and socioeconomic status, confirmation of preexisting cardiovascular and cerebrovascular disease, an...
OBJECTIVES We sought to characterize the predictors of incident congestive heart failure (CHF), as determined by central adjudication, in a community-based elderly population. BACKGROUND The elderly constitute a growing proportion of patients admitted to the hospital with CHF, and CHF is a leading source of morbidity and mortality in this group. Elderly patients differ from younger individuals diagnosed with CHF in terms of biologic characteristics. METHODS We analyzed data from the Cardiovascul...
Abstract —Left ventricular (LV) hypertrophy and concentric remodeling have been defined by using a variety of indexation methods and partition values (PVs) for LV mass and relative wall thickness (RWT). The effects of these methods on the distribution of LV geometric patterns in hypertensive subjects remain unclear. Echocardiograms were obtained in 941 patients with stage I to III hypertension and LV hypertrophy by ECG. LV mass was calculated by using different methods of indexation for body siz...
Abstract null null Background null Diagnosing heart failure with preserved ejection fraction (HFpEF) is challenging. Although the H2FPEF score and HFA-PEFF algorithm have been proposed for diagnosing HFpEF, previous validation studies were conducted in stable chronic heart failure (HF). Moreover, information on their applicability in the Asian population is limited. We sought to investigate these scores' diagnostic performance for HFpEF in Japanese patients recently hospitalized due to acute dec...
Objectives null To investigate whether hemodynamic changes during balloon occlusion test (BOT) predict future heart failure (HF) deterioration after transcatheter atrial septal defect closure (tASD-closure). null Background null Midterm HF deterioration can sometimes occur after tASD-closure in adults. Whether hemodynamic changes during tASD-closure can help identify patients at risk is unknown. null Methods null This prospective observational study enrolled 86 consecutive adult patients who und...
Last. Julie R. McMullen(Baker IDI Heart and Diabetes Institute)H-Index: 45
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Atrial enlargement in response to pathological stimuli (e.g., hypertension, mitral valve disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude, but the diseased enlarged atria is associated with complications such as atrial fibrillation (AF), whereas physiological atrial enlargement is not. Pathological atrial enlargement and AF is also observed in a small percentage of athletes undergoing extreme/intense endurance sport and pregnant women with preeclampsia. Dif...
#1Molli Kiran(Sree Chitra Thirunal Institute for Medical Sciences and Technology)
#2Satyajeet Misra(Sree Chitra Thirunal Institute for Medical Sciences and Technology)H-Index: 6
Last. Thomas Koshy(Sree Chitra Thirunal Institute for Medical Sciences and Technology)H-Index: 6
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Abstract Objective: The primary objective of this study was to establish “normal” right atrial (RA) indexed end-systolic volumes (ESV) and emptying fraction (EF) in children undergoing ventricular septal defect (VSD) repair using 2-dimensional (2D) transesophageal echocardiography (TEE). Secondary objectives were to obtain RA indexed ESV and EF in children with RA/right ventricle (RV) volume overload {atrial septal defect (ASD)} and RV pressure overload {tetralogy of Fallot (TOF)} and to determi...
Atrial cardiomyopathy (ACM) represents a constantly evolving concept, with increasing importance in contemporary research and clinical practice. A better understanding of the mechanisms involved in atrial remodeling and its clinical correlations especially with atrial fibrillation (AF) and other cardiometabolic comorbidities may induce a significant impact on the diagnosis, prognosis, and therapeutic approach of ACM-related comorbidities. Although initially described several decades ago, investi...
Introduction: The most efficient risk stratification algorithms are expected to deliver robust and indefectible identification of high-risk children with hypertrophic cardiomyopathy (HCM). Here we compare algorithms for risk stratification in primary prevention in HCM children and investigate whether novel indices of biatrial performance improve these algorithms. Methods and Results: The endpoints were defined as sudden cardiac death, resuscitated cardiac arrest, or appropriate implantable cardi...
Abstract Background The palpation of the apex beat, one of the most fundamental physical examinations, provides a clue to left ventricular (LV) dilatation and hypertrophy; however, its relation to left atrial (LA) volume has rarely been investigated. Methods The clinical value of the apex beat, especially in relation to LA volume was studied in 138 consecutive patients. Patients were examined in the supine position for a palpable apex beat. When an apex beat was felt, the apex beat distance, def...
Objectives Repair outcomes of tricuspid regurgitation (TR) associated with ischaemic mitral regurgitation (IMR) are inferior to functional TR in terms of TR recurrence and right ventricular (RV) reverse remodelling. Our objective is to analyse right versus left heart reverse remodelling after surgery for IMR-associated TR. Methods From 2001 to 2011, 568 patients with severe IMR underwent mitral valve surgery (repair 87%, replacement 13%), and 131 had concomitant tricuspid valve repair. Median fo...
Abstract Objectives This study is to establish the association of left atrial reservoir strain (LARS) with incident heart failure (HF), and the impact of substituting LARS for left atrial (LA) volume index (LAVI) in diastolic assessment. Background LARS measures passive LA stretch and is a sensitive marker of left ventricular diastolic dysfunction (DD). The potential contribution of LARS to diastolic assessment is unclear. Methods Baseline clinical and echocardiographic assessments were obtained...
#1Liza Thomas(UNSW: University of New South Wales)H-Index: 30
#2Denisa Muraru(University of Milano-Bicocca)H-Index: 35
Last. Luigi P. Badano(University of Milano-Bicocca)H-Index: 69
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Left atrial (LA) structural and functional evaluation have recently emerged as powerful biomarkers for adverse events in a variety of cardiovascular conditions. Moreover, noninvasive evaluation of LA pressure has gained importance in the characterization of the hemodynamic profile of patients. This review describes the methodology, benefits and pitfalls of measuring LA size and function by echocardiography and provides a brief overview of the prognostic utility of newer echocardiographic metrics...