American Journal of Cardiology
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#1Dennis Grewal (LLUMC: Loma Linda University Medical Center)
#1Dennis Grewal (LLUMC: Loma Linda University Medical Center)
Last. Dmitry Abramov (LLUMC: Loma Linda University Medical Center)H-Index: 3
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Despite significant advances in evidence-based treatments for heart failure with reduced ejection fraction (HFrEF), the use of guideline directed medical therapy (GDMT) at recommended doses remains suboptimal. We examine the usage and modification of inpatient GDMT and its effect on outcomes in patients hospitalized with a diagnosis of acute on chronic HFrEF between 2013 and 2018. Overall use and modification of GDMT, which included heart failure appropriate beta-blockers (BB), renin-angiotensin...
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#1Ethan J. Rowin (Tufts Medical Center)H-Index: 26
#2Barry J. Maron (Tufts Medical Center)H-Index: 169
Last. Martin S. Maron (Tufts Medical Center)H-Index: 70
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While predicting prognosis to anticipate adverse disease course has long been an aspiration in hypertrophic cardiomyopathy (HC), reliable markers of progressive and unrelenting heart failure symptoms in the absence of obstruction are not well characterized. We sought to evaluate markers of systolic function, including the role of global longitudinal strain (GLS), to identify nonobstructive HC patients at risk for future heart failure. A cohort of 296 consecutive nonobstructive HC patients (42 ± ...
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#1Tove Hygrell (KI: Karolinska Institutet)
#2Martin Stridh (Lund University)H-Index: 24
Last. Emma Svennberg (Karolinska University Hospital)H-Index: 2
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The aim of this study was to establish the prevalence and prognostic implication of progressive supraventricular arrhythmias from frequent supraventricular ectopic complexes, isolated, in bi- or trigeminy, to supraventricular tachycardias with different characteristics. In the STROKESTOP I mass-screening study for atrial fibrillation (AF) in 75- and 76-year olds in Sweden, participants registered 30-second intermittent ECG twice daily for two weeks. The ECG-recordings from STROKESTOP I were re-e...
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#1Rachel Blumel (Yale University)
#2Kanchi Patel (Yale University)H-Index: 1
Last. John A. Elefteriades (Yale University)H-Index: 77
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We have noticed, in caring for thousands of patients with ascending aortic aneurysm (AscAA), that the "thumb palm test" is often positive (with the thumb crossing beyond the edge of the palm). It is not known how accurate this test may be. We conducted the thumb-palm test in 305 patients undergoing cardiac surgery with intra-operative transesophageal echocardiography (TEE) for a variety of disorders: ascending aneurysm in 59 (19.4%) and non-AscAA disease in 246 (80.6%) (including CABG, valve rep...
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#1Pil Sang Song (CNU: Chungnam National University)H-Index: 11
#2Yong Hwan Park (SKKU: Sungkyunkwan University)H-Index: 13
Last. Joo-Yong Hahn (SMC: Samsung Medical Center)H-Index: 29
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Controversy remains regarding the optimal antiplatelet regimen in patients with acute coronary syndrome (ACS). This study sought to investigate the efficacy and safety of P2Y12 inhibitor monotherapy compared with conventional dual antiplatelet therapy (DAPT) and aspirin monotherapy in patients with ACS undergoing percutaneous coronary intervention. Data on 4,453 patients were pooled from SMART-DATE and SMART-CHOICE randomized trials. Antiplatelet therapy regimens were categorized as P2Y12 inhibi...
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#1Alan Rozanski (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 18
#1Alan Rozanski (Cedars-Sinai Medical Center)H-Index: 65
Last. Daniel S. Berman (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 1
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Adverse health behaviors are potent drivers of chronic disease and premature mortality. This has led to the development of various lifestyle scores to predict clinical risk, but their complexity makes them impractical for use in clinical settings. Thus, there is a need to develop a brief lifestyle score that can assess factors such as exercise and diet within the constraints of routine medical practice. Accordingly, we assessed 19,081 patients undergoing coronary artery calcium (CAC) scanning be...
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#1Kevin L. Kelly (Mayo Clinic)H-Index: 2
#2Robert J. Wentz (Mayo Clinic)H-Index: 7
Last. Wayne L. Miller (Mayo Clinic)H-Index: 29
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Heart failure (HF) commonly progresses over time and identifying differences in volume profiles may help stratify risk and guide therapy. The aim of this study was to assess the pathophysiologic and prognostic roles of volume profiles for HF progression in stable ambulatory and hospitalized patients. HF patients who had undergone quantitative intravascular volume analysis (185 outpatients and 139 inpatients) were retrospectively assessed for the combined end point of HF-related hospital admissio...
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#1Alexandros Briasoulis (UoA: National and Kapodistrian University of Athens)H-Index: 26
#2Toshiki Kuno (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 12
Last. Hiroki Ueyama (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 5
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#1Michelle D. Kelsey (Duke University)
#2Courtney Page (Durham University)H-Index: 1
Last. Neha J. Pagidipati (Duke University)H-Index: 18
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Lipoprotein (a) [Lp(a)] is associated with increased risk of atherosclerotic cardiovascular disease (ASCVD). As directed therapy for Lp(a) emerges, it is important to understand patterns of Lp(a) testing in routine clinical practice. We set out to characterize Lp(a) testing across a large academic health system. Using electronic health record (EHR) data from 2014 to 2019, we compared patients who underwent Lp(a) testing to date-matched peers who had low density lipoprotein (LDL-C) assessment alo...
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Coronary artery disease
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