Management of High-Risk Localised Prostate Cancer

High-risk localised prostate cancer (PCa) is defined as significant likelihood of death from PCa or development of distant metastases. It is important to identify patients at high risk of progression who may benefit from neoadjuvant or adjuvant therapies. To review definitions for high-risk localised PCa and review outcomes of different treatment modalities. Randomised and nonrandomised clinical trials addressing the characterisation of patients...