High selectivity and sensitivity sensor based on MIP and SPR in tapered plastic optical fibers for the detection of l-nicotine

A biomimetic sensor based on molecularly imprinted polymer (MIP) and surface plasmon resonance (SPR) transduction, in connection with tapered plastic optical fiber (POF), has been developed for the marker-free, direct and selective detection of low molecular weight substances. The device has been experimentally tested for l-nicotine ((−)-1-methyl-2-(3-pyridyl)pyrrolidine, MW = 162.24). The sensor system developed made the selective and fast...