Original paper
Avidity of anti-glomerular basement membrane autoantibodies was associated with disease severity
Abstract
Anti-glomerular basement membrane (GBM) antibody-mediated diseases are characterized by the binding of autoantibodies to GBM, leading to rapidly progressive glomerulonephritis that often results in irreversible loss of renal function. The nephrotoxic potential of anti-GBM antibodies has been demonstrated in animal experiments. We questioned whether high avidity leads to persistent deposition of anti-GBM antibodies, thereby perpetuating...
Paper Details
Title
Avidity of anti-glomerular basement membrane autoantibodies was associated with disease severity
Published Date
Jul 1, 2005
Journal
Volume
116
Issue
1
Pages
77 - 82
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Notes
History