This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.
Original paper

Betulin-Derived Compounds as Inhibitors of Alphavirus Replication

Volume: 72, Issue: 11, Pages: 1917 - 1926
Published: Oct 19, 2009
Abstract
This paper describes inhibition of Semliki Forest virus (SFV) replication by synthetic derivatives of naturally occurring triterpenoid betulin (1). Chemical modifications were made to OH groups at C-3 and C-28 and to the C-20−C-29 double bond. A set of heterocyclic betulin derivatives was also assayed. A free or acetylated OH group at C-3 was identified as an important structural contributor for anti-SFV activity, 3,28-di-O-acetylbetulin (4)...
Paper Details
Title
Betulin-Derived Compounds as Inhibitors of Alphavirus Replication
Published Date
Oct 19, 2009
Volume
72
Issue
11
Pages
1917 - 1926
© 2025 Pluto Labs All rights reserved.
Step 1. Scroll down for details & analytics related to the paper.
Discover a range of citation analytics, paper references, a list of cited papers, and more.