Matrix metalloproteinases in stem cell regulation and cancer
Abstract
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenolytic enzymes during amphibian tadpole morphogenesis in 1962, this intriguing family of extracellular proteinases has been implicated in various processes of developmental biology. However, the pathogenic roles of MMPs in human diseases such as cancer have also garnered widespread attention. The most straightforward explanation for their role in...
Paper Details
Title
Matrix metalloproteinases in stem cell regulation and cancer
Published Date
May 1, 2015
Journal
Volume
44-46
Pages
184 - 190
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Notes
History