Review paper
Epithelial-Mesenchymal Transitions in Development and Disease
Abstract
The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and in the differentiation of multiple tissues and organs. EMT also contributes to tissue repair, but it can adversely cause organ fibrosis and promote carcinoma progression through a variety of mechanisms. EMT endows cells with migratory and invasive properties, induces stem cell properties, prevents apoptosis and senescence, and contributes to...
Paper Details
Title
Epithelial-Mesenchymal Transitions in Development and Disease
Published Date
Nov 1, 2009
Journal
Volume
139
Issue
5
Pages
871 - 890
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