Original paper
Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance.
Abstract
We report here a murine model for experimental chronic colitis where administration of trinitrobenzene sulfonic acid (TNBS) in 50% ethanol induced inflammation of large intestine in susceptible (C3H/HeJ and BALB/c) but not resistant (C57BL/6 and DBA/2) mouse strains. We queried whether mucosal trinitrophenyl (TNP)-specific B cell responses were induced in mice with TNBS-induced colitis, and if induction of tolerance to TNBS by oral...
Paper Details
Title
Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance.
Published Date
Sep 1, 1996
Journal
Volume
157
Issue
5
Pages
2174 - 2185
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Notes
History