Review paper
Phenome-wide analysis of genome-wide polygenic scores
Abstract
Genome-wide polygenic scores (GPS), which aggregate the effects of thousands of DNA variants from genome-wide association studies (GWAS), have the potential to make genetic predictions for individuals. We conducted a systematic investigation of associations between GPS and many behavioral traits, the behavioral phenome. For 3152 unrelated 16-year-old individuals representative of the United Kingdom, we created 13 GPS from the largest GWAS for...
Paper Details
Title
Phenome-wide analysis of genome-wide polygenic scores
Published Date
Aug 25, 2015
Journal
Volume
21
Issue
9
Pages
1188 - 1193
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