Late-breaking abstract: Oral corticosteroid-sparing effect of mepolizumab in severe eosinophilic asthma: The SIRIUS study

Background: null There is an unmet treatment need in a sub-population of severe asthma patients who, despite the use of maximal inhaled therapy, require regular treatment with oral corticosteroids (OCS). null null Objective: null To study the steroid-sparing effect of mepolizumab in severe eosinophilic asthma. null null Methods: null We conducted a randomized, double-blind placebo controlled trial of mepolizumab (n=69) administered as monthly...