Original paper
Reproduction of transfusion-related acute lung injury in an ex vivo lung model [see comments]
Abstract
Leukoagglutinins are implicated in transfusion-related acute lung injury (TRALI). In the present study, severe lung vascular leakage was reproduced by application of a leukoagglutinating antibody of anti-5b specificity in an ex vivo lung model. The antibody originated from a multiparous donor-plasma, observed to cause noncardiogenic edema during transfusion therapy. Heated full plasma (anti-5b-titer 1/128) or purified immunoglobulin G fraction...
Paper Details
Title
Reproduction of transfusion-related acute lung injury in an ex vivo lung model [see comments]
Published Date
Oct 1, 1990
Journal
Volume
76
Issue
7
Pages
1438 - 1444
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Notes
History