THE ORAL-FACIAL-DIGITAL SYNDROME: A MULTIPLE CONGENITAL CONDITION OF FEMALES WITH ASSOCIATED CHROMOSOMAL ABNORMALITIES

The oral-facial-digital (OFD) syndrome is a congenital condition found only in females and with variable anomalies of the oral, facial, and digital tissues. Defects of the oral region are fairly constant, while involvement of the face and digits may, or may not, be found. Radiographic and cephalometric analyses reveal syndrome-specific characteristics of the skull and digital bones. Alopecia, coarse skin, and minimal hypotelorism may be present....