Notch signaling in prostate cancer: A moving target

By regulating cell fate, proliferation, and survival, Notch pathway signaling provides critical input into differentiation, organization, and function of multiple tissues. Notch signaling is also becoming an increasingly recognized feature in malignancy, including prostate cancer, where it may play oncogenic or tumor suppressive roles.Based on an electronic literature search from 2000 to 2013 we identified, summarized, and integrated published...