The Prostate
Papers 5,407
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#1Nichujie Li (CSU: Central South University)
#2Wei-Jie Song (CSU: Central South University)
Last. Leye He (CSU: Central South University)H-Index: 6
view all 7 authors...
OBJECTIVE To evaluate the prognostic nutritional index (PNI) in predicting the biochemical recurrence (BCR) of patients treated with robot-assisted laparoscopic radical prostatectomy (RALP). METHODS The clinical data of 136 patients treated with RALP in the Department of Urology, The Third Xiangya Hospital of Central South University were retrospectively analyzed. The endpoint of observation was BCR. The area under the receiver operating characteristic (ROC) curve was evaluated to determine the ...
#1Pubordee Aussavavirojekul (MU: Mahidol University)
#2Apirak Hoonlor (MU: Mahidol University)H-Index: 5
Last. Sittiporn Srinualnad (MU: Mahidol University)H-Index: 5
view all 3 authors...
BACKGROUND Due to the low cancer-detection rate in patients with PIRADS category 3 lesions, we created machine learning (ML) models to facilitate decision-making about whether to perform prostate biopsies or monitor clinical information without biopsy results. METHODS In our retrospective, single-center study, 101 eligible patients with at least one PIRADS category 3 lesion but no higher PIRADS lesions underwent MRI/US fusion biopsies between September 2017 and June 2020. Thirty additional patie...
#1Mari Nakazawa (JHU: Johns Hopkins University)H-Index: 1
#2Mike Fang (CWRU: Case Western Reserve University)H-Index: 5
Last. Emmanuel S. Antonarakis (University of Minnesota)
view all 6 authors...
Background null Inactivating missense mutations in the SPOP gene, encoding speckle-type poxvirus and zinc-finger protein, are one of the most common genetic alterations in prostate cancer. null Methods null We retrospectively identified 72 consecutive prostate cancer patients with somatic SPOP mutations, through next-generation sequencing analysis, who were treated at the Johns Hopkins Hospital. We evaluated clinical and genomic characteristics of this SPOP-mutant subset. null Results null SPOP ...
#1Anne Merete Aaland Tryggestad (Oslo University Hospital)H-Index: 4
#2Karol Axcrona (Oslo University Hospital)H-Index: 18
Last. Gunnar Kvalheim (Oslo University Hospital)H-Index: 48
view all 19 authors...
Background null Patients with high-risk prostate cancer (PC) can experience biochemical relapse (BCR), despite surgery, and develop noncurative disease. The present study aimed to reduce the risk of BCR with a personalized dendritic cell (DC) vaccine, given as adjuvant therapy, after robot-assisted laparoscopic prostatectomy (RALP). null Methods null Twelve weeks after RALP, 20 patients with high-risk PC and undetectable PSA received DC vaccinations for 3 years or until BCR. The primary endpoint...
#1Andrea K. Miyahira (PCF: Prostate Cancer Foundation)H-Index: 8
#2Jelani C. Zarif (Johns Hopkins Medicine)H-Index: 10
Last. Howard R. Soule (PCF: Prostate Cancer Foundation)H-Index: 15
view all 10 authors...
INTRODUCTION The 2021 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, "Prostate Cancer Research in the 21st Century," was held virtually, from June 24-25, 2021. METHODS The CHPCA Meeting is organized by the Prostate Cancer Foundation as a unique discussion-oriented meeting focusing on critical topics in prostate cancer research envisioned to bridge the next major advances in prostate cancer biology and treatment. The 2021 CHPCA Meeting was virtually attended by 89 investigators and includ...
#1Julian Hanske (RUB: Ruhr University Bochum)H-Index: 16
#2Yannic Risse (RUB: Ruhr University Bochum)
Last. Marko Brock (RUB: Ruhr University Bochum)H-Index: 12
view all 10 authors...
BACKGROUND Magnetic resonance imaging (MRI)-targeted prostate biopsy is a routinely used diagnostic tool for prostate cancer (PCa) detection. However, a clear superiority of the optimal approach for software-based MRI processing during biopsy procedures is still unanswered. To investigate the impact of robotic approach and software-based image processing (rigid vs. elastic) during MRI/transrectal ultrasound (TRUS) fusion prostate biopsy (FBx) on overall and clinically significant (cs) PCa detect...
#1Zhipeng Wang (SCU: Sichuan University)H-Index: 35
#2Sha Zhu (SCU: Sichuan University)H-Index: 8
Last. Yuchao Ni (SCU: Sichuan University)H-Index: 4
view all 21 authors...
BACKGROUND To explore whether metastatic castration-resistant prostate cancer (mCRPC) patients with distinct intraductal carcinoma of the prostate (IDC-P) subtypes respond differently to abiraterone and docetaxel treatment. METHODS We retrospectively analyzed data of 170 mCRPC patients receiving abiraterone or docetaxel as first-line therapy. PSA response, PSA progression-free survival (PSA-PFS), radiographic progression-free survival (rPFS), and overall survival (OS) were analyzed based on the ...
#1Belinda L. Sun (UA: University of Arizona)H-Index: 4
Prostate cancer is the second most common cause of cancer-related death in men in the United States and the fifth worldwide. Most prostate cancer arises as an androgen-dependent tumor but eventually progresses into castration-resistance prostate cancer, incurable by the current androgen deprivation therapy and chemotherapy. The development of immunotherapy in cancer treatment has brought an exciting era of antiprostate cancer therapy through antitumor immune responses. Prostate cancer is recogni...
#1Michael Siedow (OSUMC: The Ohio State University Wexner Medical Center)H-Index: 1
#2Mariah Eisner (OSU: The Ohio State University)
Last. D.A. Diaz (OSUMC: The Ohio State University Wexner Medical Center)H-Index: 1
view all 9 authors...
BACKGROUND The Gleason scoring system is the most widely used method to assess prostate adenocarcinoma pathology however interobserver variability is significant. Gleason score, PSA level, and clinical stage comprise the NCCN risk stratification that guides treatment decision making. Given the importance of an accurate Gleason score and wide interobserver variability, referral centers routinely review outside pathology at the time of consultation. We sought to address the impact a secondary path...
#1M. DroghettiH-Index: 3
#2Angelo PorrecaH-Index: 17
Last. Eugenio BrunocillaH-Index: 28
view all 11 authors...
INTRODUCTION AND OBJECTIVES Holmium laser enucleation of prostate (HoLEP) represents one of the most studied surgical techniques for benign prostatic hyperplasia (BPH). Its efficacy in symptom relief has been widely depicted. However, few evidence is available regarding the possible predictors of symptom recurrence. We aimed to evaluate long-term outcomes, symptom recurrence rate, and predictors in patients that underwent HoLEP. MATERIALS AND METHODS We retrospectively analyzed data from patient...
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