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Original paper

Activation of PAR2 receptors sensitizes primary afferents and causes leukocyte rolling and adherence in the rat knee joint

Volume: 167, Issue: 8, Pages: 1665 - 1678
Published: Jul 31, 2012
Abstract
Background and Purpose The PAR 2 receptors are involved in chronic arthritis by mechanisms that are as yet unclear. Here, we examined PAR 2 activation in the rat knee joint. Experimental Approach PAR 2 in rat knee joint dorsal root ganglia ( DRG ) cells at L 3‐ L 5, retrogradely labelled with Fluoro‐gold ( FG ) were demonstrated immunohistochemically. Electrophysiological recordings from knee joint nerve fibres in urethane anaesthetized Wistar...
Paper Details
Title
Activation of PAR2 receptors sensitizes primary afferents and causes leukocyte rolling and adherence in the rat knee joint
Published Date
Jul 31, 2012
Volume
167
Issue
8
Pages
1665 - 1678
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