Original paper
A vectorized sequence-coupling model for predicting HIV protease cleavage sites in proteins
Volume: 268, Issue: 23, Pages: 16938 - 16948
Published: Aug 1, 1993
Abstract
What kind of peptide sequences can be cleaved by HIV protease, and what kind cannot be? This is a crucially important problem in designing effective inhibitors against HIV protease as potential drugs for AIDS therapy. To tackle this problem, a sequence-coupling and vectorized model is proposed for predicting the cleavability of oligopeptides by proteases with multiple and extended specificity subsites. In comparison with existing methods, the...
Paper Details
Title
A vectorized sequence-coupling model for predicting HIV protease cleavage sites in proteins
Published Date
Aug 1, 1993
Volume
268
Issue
23
Pages
16938 - 16948
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Notes
History