Original paper
Forging a signature of in vivo senescence
Abstract
'Cellular senescence', a term originally defining the characteristics of cultured cells that exceed their replicative limit, has been broadened to describe durable states of proliferative arrest induced by disparate stress factors. Proposed relationships between cellular senescence, tumour suppression, loss of tissue regenerative capacity and ageing suffer from lack of uniform definition and consistently applied criteria. Here, we highlight...
Paper Details
Title
Forging a signature of in vivo senescence
Published Date
Jun 24, 2015
Journal
Volume
15
Issue
7
Pages
397 - 408
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Notes
History