Review paper
NODs: intracellular proteins involved in inflammation and apoptosis
Abstract
NOD (nucleotide-binding oligomerization domain) proteins are members of a family that includes the apoptosis regulator APAF1 (apoptotic protease activating factor 1), mammalian NOD-LRR (leucine-rich repeat) proteins and plant disease-resistance gene products. Several NOD proteins have been implicated in the induction of nuclear factor-κB (NF-κB) activity and in the activation of caspases. Two members of the NOD family, NOD1 and NOD2, mediate the...
Paper Details
Title
NODs: intracellular proteins involved in inflammation and apoptosis
Published Date
May 1, 2003
Journal
Volume
3
Issue
5
Pages
371 - 382
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