Open Biology
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#1Yuhei Nishimura (Mie University)H-Index: 24
#2Daishi Yamakawa (Mie University)H-Index: 6
Last. Masaki Inagaki (Mie University)H-Index: 81
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Primary cilia, antenna-like structures of the plasma membrane, detect various extracellular cues and transduce signals into the cell to regulate a wide range of functions. Lipid rafts, plasma membr...
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#1Janna N. Schultzhaus (NRL: United States Naval Research Laboratory)H-Index: 7
#2William Judson Hervey (NRL: United States Naval Research Laboratory)H-Index: 6
Last. Christopher M. Spillmann (NRL: United States Naval Research Laboratory)H-Index: 21
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Barnacles interest the scientific community for multiple reasons: their unique evolutionary trajectory, vast diversity and economic impact—as a harvested food source and also as one of the most pro...
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#1Devin Clarke (University of Sussex)H-Index: 2
#2Hans S. Crombag (University of Sussex)H-Index: 28
Last. Catherine Hall (University of Sussex)H-Index: 13
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Changes in microglial morphology are powerful indicators of the inflammatory state of the brain. Here, we provide an open-source microglia morphology analysis pipeline that first cleans and registe...
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#1Lucy Remnant (Edin.: University of Edinburgh)H-Index: 2
#2Natalia Y. Kochanova (Edin.: University of Edinburgh)
Last. William C. Earnshaw (Edin.: University of Edinburgh)H-Index: 127
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Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review some of t...
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#1Silje Anda (Oslo University Hospital)H-Index: 4
#2Erik Boye (Oslo University Hospital)H-Index: 35
Last. Beáta Grallert (Oslo University Hospital)H-Index: 20
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Cellular asymmetry plays a major role in the ageing and evolution of multicellular organisms. However, it remains unknown how the cell distinguishes ‘old’ from ‘new’ and whether asymmetry is an att...
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#1Consuelo Coronel Arrechea (CONICET: National Scientific and Technical Research Council)
#2María Luz Giolito (CONICET: National Scientific and Technical Research Council)
Last. Javier Valdez Taubas (CONICET: National Scientific and Technical Research Council)
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Protein S-acylation or palmitoylation is a widespread post-translational modification that consists of the addition of a lipid molecule to cysteine residues of proteins through a thioester bond. Pa...
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Histone H1s or the linker histones are a family of dynamic chromatin compacting proteins that are essential for higher-order chromatin organization. These highly positively charged proteins were pr...
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#1Joshua Wang (QUT: Queensland University of Technology)H-Index: 1
#2Kate Beecher (QUT: Queensland University of Technology)H-Index: 5
There is accumulating evidence that an obesogenic Western diet causes neuroinflammatory damage to the brain, which then promotes further appetitive behaviour. Neuroinflammation has been extensively...
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#1Meek Rw (Ebor: University of York)
#2Ian T. Cadby (University of Birmingham)H-Index: 7
Last. Andrew L. Lovering (University of Birmingham)H-Index: 28
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Glycolysis and gluconeogenesis are central pathways of metabolism across all domains of life. A prominent enzyme in these pathways is phosphoglucose isomerase (PGI), which mediates the interconversion of glucose-6-phosphate and fructose-6-phosphate. The predatory bacterium Bdellovibrio bacteriovorus leads a complex life cycle, switching between intraperiplasmic replicative and extracellular 'hunter' attack-phase stages. Passage through this complex life cycle involves different metabolic states....
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#1Grace K. Chan ('KCL': King's College London)
#2John A. McGrath ('KCL': King's College London)H-Index: 86
Last. Maddy Parsons ('KCL': King's College London)H-Index: 37
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Epidermal growth factor receptor (EGFR) plays a critical role in the promotion of epithelial cell proliferation and migration. Previous studies have suggested a cooperative role between EGFR and integrin signalling pathways that enable efficient adhesion and migration but the mechanisms controlling this remain poorly defined. Here, we show that EGFR forms a complex with focal adhesion kinase in epithelial cells. Surprisingly, this complex enhances local Src activity at focal adhesions to promote...
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