If this was not happening in the midst of the COVID-19 pandemic, I imagine that I would be speaking these words instead of writing them on my laptop. Even so, I am so jazzed for this opportunity! N...
#1Sandra L. Wolin(NIH: National Institutes of Health)H-Index: 55
I am so very honored to receive the Women in Cell Biology Sandra K. Masur Senior Leadership Award from the American Society for Cell Biology (ASCB), particularly because many of the previous awarde...
#1Sandra K. Masur(ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 18
#2Ursula Goodenough(WashU: Washington University in St. Louis)H-Index: 63
Last. Julia Omotade(Association of American Medical Colleges)
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It’s been 50 years since Women in Cell Biology (WICB) was founded by junior women cell biologists who found themselves neither represented at the American Society for Cell Biology (ASCB) presentati...
The ability of cells to sense chemical gradients is essential during development, morphogenesis, and immune responses. Although much is known about chemoattraction, chemorepulsion remains poorly understood. Proliferating Dictyostelium cells secrete a chemorepellent protein called AprA. AprA prevents pseudopod formation at the region of the cell closest to the source of AprA, causing the random movement of cells to be biased away from the AprA. Activation of Ras proteins in a localized sector of ...
Class III myosins are actin-based motors proposed to transport cargo to the distal tips of stereocilia in the inner ear hairs cells and/or to participate in stereocilia length regulation, which is especially important during development. Mutations in the MYO3A gene are associated with delayed onset deafness. A previous study demonstrated that L697W, a dominant deafness mutation, disrupts MYO3A ATPase and motor properties but does not impair its ability to localize to the tips of actin protrusion...
Here we report on the related TBC/RabGAPs EPI64A and EPI64B and show that they function to organize the apical aspect of epithelial cells. EPI64A binds the scaffolding protein EBP50/NHERF1, which itself binds active ezrin in epithelial cell microvilli. Epithelial cells additionally express EPI64B that also localizes to microvilli. However, EPI64B does not bind EBP50 and both proteins are shown to have a microvillar localization domain that spans the RabGAP domains. CRISPR/Cas9 was used to inacti...
#2Fengzhi Jin(FSU: Florida State University)H-Index: 9
Last. Yanchang Wang(FSU: Florida State University)H-Index: 25
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A pathway required for the efficient recovery from DNA replication stress in budding yeast was uncovered. During this recovery, PP2A promotes the sequential reversal of Cdk1 phosphorylation by Swe1...
#1Rushika M. Perera(UCSF: University of California, San Francisco)H-Index: 26
Today’s cell biology could be considered a fusion of disciplines that blends advanced genetics, molecular biology, biochemistry, and engineering to answer fundamental as well as medically relevant ...
I am honored to receive the E. E. Just Award. I applaud ASCB’s commitment to recognizing the contributions of researchers from historically excluded racial and ethnic groups and appreciate my inclu...
I am incredibly honored to receive the 2021 WICB Junior Award for Excellence in Research in WICB’s golden jubilee year. In this essay, I traverse my scientific journey starting with my PhD, highlig...
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